Publications

I. Singh, W. M. Oldham, F. N. Rahaghi (2020). Precision Medicine in Pulmonary Hypertension. Precision in Pulmonary, Critical Care, and Sleep Medicine.

V. A. Guarino, W. M. Oldham, J. Loscalzo, Y. Y. Zhang (2019). Reaction Rate of Pyruvate and Hydrogen Peroxide: Assessing Antioxidant Capacity of Pyruvate under Biological Conditions. Scientific Reports.

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I. Singh, R. K. F. Oliveira, R. Naeije, F. N. Rahaghi, W. M. Oldham, D. M. Systrom, A. B. Waxman (2019). Pulmonary Vascular Distensibility and Early Pulmonary Vascular Remodeling in Pulmonary Hypertension. Chest.

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R. M. Sternschein, W. M. Oldham (2019). Paradoxical Embolization via Large Pulmonary Arteriovenous Malformation. American Journal of Respiratory and Critical Care Medicine.

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T. Bertero, W. M. Oldham, E. M. Grasset, I. Bourget, E. Boulter, S. Pisano, P. Hofman, F. Bellvert, G. Meneguzzi, D. V. Bulavin, S. Estrach, C. C. Feral, S. Y. Chan, A. Bozec, C. Gaggioli (2019). Tumor-Stroma Mechanics Coordinate Amino Acid Availability to Sustain Tumor Growth and Malignancy. Cell Metabolism.

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E. Y. Kim, W. M. Oldham (2019). Innate T Cells in the Intensive Care Unit. Molecular Immunology.

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E. E. Verwer, T. R. Kavanagh, W. J. Mischler, Y. Feng, K. Takahashi, S. Wang, T. M. Shoup, R. Neelamegam, J. Yang, N. J. Guehl, C. Ran, W. Massefski, Y. Cui, S. El-Chemaly, P. M. Sadow, W. M. Oldham, M. F. Kijewski, G. El Fakhri, M. D. Normandin, C. Priolo (2018). [¹⁸F]Fluorocholine and [¹⁸F]Fluoroacetate PET as Imaging Biomarkers to Assess Phosphatidylcholine and Mitochondrial Metabolism in Preclinical Models of TSC and LAM. Clinical Cancer Research.

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R. S. Wang, W. M. Oldham, B. A. Maron, J. Loscalzo (2018). Systems Biology Approaches to Redox Metabolism in Stress and Disease States. Antioxidants & Redox Signaling.

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M. M. Musri, N. Coll-Bonfill, B. A. Maron, V. I. Peinado, R. S. Wang, J. Altirriba, I. Blanco, W. M. Oldham, O. Tura-Ceide, J. Garcia-Lucio, B. de la Cruz-Thea, G. Meister, J. Loscalzo, J. A. Barbera (2018). MicroRNA Dysregulation in Pulmonary Arteries from Chronic Obstructive Pulmonary Disease. Relationships with Vascular Remodeling. American Journal of Respiratory Cell and Molecular Biology.

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J. S. Yang, J. W. Hsu, S. Y. Park, J. Li, W. M. Oldham, G. V. Beznoussenko, A. A. Mironov, J. Loscalzo, V. W. Hsu (2018). GAPDH Inhibits Intracellular Pathways during Starvation for Cellular Energy Homeostasis. Nature.

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A. O. Samokhin, T. Stephens, B. M. Wertheim, R. S. Wang, S. O. Vargas, L. M. Yung, M. Cao, M. Brown, E. Arons, P. B. Dieffenbach, J. G. Fewell, M. Matar, F. P. Bowman, K. J. Haley, G. A. Alba, S. M. Marino, R. Kumar, I. O. Rosas, A. B. Waxman, W. M. Oldham, D. Khanna, B. B. Graham, S. Seo, V. N. Gladyshev, P. B. Yu, L. E. Fredenburgh, J. Loscalzo, J. A. Leopold, B. A. Maron (2018). NEDD9 Targets COL3A1 to Promote Endothelial Fibrosis and Pulmonary Arterial Hypertension. Science Translational Medicine.

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W. M. Oldham, R. K. F. Oliveira, R. S. Wang, A. R. Opotowsky, D. M. Rubins, J. Hainer, B. M. Wertheim, G. A. Alba, G. Choudhary, A. Tornyos, C. A. MacRae, J. Loscalzo, J. A. Leopold, A. B. Waxman, H. Olschewski, G. Kovacs, D. M. Systrom, B. A. Maron (2018). Network Analysis to Risk Stratify Patients With Exercise Intolerance. Circulation Research.

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W. M. Oldham (2018). The Long Noncoding RNA LnRPT Puts the Brakes on Pulmonary Artery Smooth Muscle Cell Proliferation. American Journal of Respiratory Cell and Molecular Biology.

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J. P. Fessel, W. M. Oldham (2018). Pyridine Dinucleotides from Molecules to Man. Antioxidants & Redox Signaling.

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J. P. Fessel, W. M. Oldham (2018). Nicotine Adenine Dinucleotides: The Redox Currency of the Cell. Antioxidants & Redox Signaling.

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H. C. Lam, H. J. Liu, C. V. Baglini, H. Filippakis, N. Alesi, J. Nijmeh, H. Du, A. L. Lope, K. A. Cottrill, A. Handen, J. M. Asara, D. J. Kwiatkowski, I. Ben-Sahra, W. M. Oldham, S. Y. Chan, E. P. Henske (2017). Rapamycin-Induced miR-21 Promotes Mitochondrial Homeostasis and Adaptation in mTORC1 Activated Cells. Oncotarget.

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H. C. Lam, C. V. Baglini, A. L. Lope, A. A. Parkhitko, H. J. Liu, N. Alesi, I. A. Malinowska, D. Ebrahimi-Fakhari, A. Saffari, J. J. Yu, A. Pereira, D. Khabibullin, B. Ogorek, J. Nijmeh, T. Kavanagh, A. Handen, S. Y. Chan, J. M. Asara, W. M. Oldham, M. T. Diaz-Meco, J. Moscat, M. Sahin, C. Priolo, E. P. Henske (2017). P62/SQSTM1 Cooperates with Hyperactive mTORC1 to Regulate Glutathione Production, Maintain Mitochondrial Integrity, and Promote Tumorigenesis. Cancer Research.

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T. Bertero, W. M. Oldham, K. A. Cottrill, S. Pisano, R. R. Vanderpool, Q. Yu, J. Zhao, Y. Tai, Y. Tang, Y. Y. Zhang, S. Rehman, M. Sugahara, Z. Qi, J. Gorcsan, S. O. Vargas, R. Saggar, R. Saggar, W. D. Wallace, D. J. Ross, K. J. Haley, A. B. Waxman, V. N. Parikh, T. De Marco, P. Y. Hsue, A. Morris, M. A. Simon, K. A. Norris, C. Gaggioli, J. Loscalzo, J. Fessel, S. Y. Chan (2016). Vascular Stiffness Mechanoactivates YAP/TAZ-Dependent Glutaminolysis to Drive Pulmonary Hypertension. Journal of Clinical Investigation.

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W. M. Oldham, J. Loscalzo (2016). Quantification of 2-Hydroxyglutarate Enantiomers by Liquid Chromatography-Mass Spectrometry. Bio Protocols.

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W. M. Oldham, G. D. Lewis, A. R. Opotowsky, A. B. Waxman, D. M. Systrom (2016). Unexplained Exertional Dyspnea Caused by Low Ventricular Filling Pressures: Results from Clinical Invasive Cardiopulmonary Exercise Testing. Pulmonary Circulation.

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B. A. Maron, T. E. Stephens, L. A. Farrell, W. M. Oldham, J. Loscalzo, J. A. Leopold, G. D. Lewis (2016). Elevated Pulmonary Arterial and Systemic Plasma Aldosterone Levels Associate with Impaired Cardiac Reserve Capacity during Exercise in Left Ventricular Systolic Heart Failure Patients: A Pilot Study. Journal of Heart and Lung Transplantation.

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J. P. Fessel, W. M. Oldham (2016). Pulmonary Hypertension as a Metabolic Disease. Pulmonary Hypertension.

N. C. Berry, A. Manyoo, W. M. Oldham, T. E. Stephens, R. H. Goldstein, A. B. Waxman, J. A. Tracy, P. J. Leary, J. A. Leopold, S. Kinlay, A. R. Opotowsky, D. M. Systrom, B. A. Maron (2015). Protocol for Exercise Hemodynamic Assessment: Performing an Invasive Cardiopulmonary Exercise Test in Clinical Practice. Pulmonary Circulation.

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W. M. Oldham, C. B. Clish, Y. Yang, J. Loscalzo (2015). Hypoxia-Mediated Increases in L-2-Hydroxyglutarate Coordinate the Metabolic Response to Reductive Stress. Cell Metabolism.

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R. S. Wang, W. M. Oldham, J. Loscalzo (2014). Network-Based Association of Hypoxia-Responsive Genes with Cardiovascular Diseases. New Journal of Physics.

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B. A. Maron, W. M. Oldham, S. Y. Chan, S. O. Vargas, E. Arons, Y. Y. Zhang, J. Loscalzo, J. A. Leopold (2014). Upregulation of Steroidogenic Acute Regulatory Protein by Hypoxia Stimulates Aldosterone Synthesis in Pulmonary Artery Endothelial Cells to Promote Pulmonary Vascular Fibrosis. Circulation.

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